化学関連資料

When formulating pharmaceuticals, it is important to understand the chemical composition and morphologies of the ingredients, as these can lead to changes in product performance. For example, active ingredient co-localisation and particle adhesion can affect the efficacy of formulation. This application note details how to use a Renishaw Raman system to conduct this type of analysis.

Application note: Combined chemical and particle distribution analysis of pharmaceutical powders

When formulating pharmaceuticals, it is important to understand the chemical composition and morphologies of the ingredients, as these can lead to changes in product performance. For example, active ingredient co-localisation and particle adhesion can affect the efficacy of formulation. This application note details how to use a Renishaw Raman system to conduct this type of analysis.

[580kB]

This note looks at incidences of polymorphism in drug development including advantages and challenges.

Application note: Using Raman spectroscopy to tackle polymorphism, an industry problem

This note looks at incidences of polymorphism in drug development including advantages and challenges.

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An application note detailing the RA802's ability to deformulate the make-up of a transdermal nicotine patch.

Application note: Raman imaging for deformulating a transdermal patch

An application note detailing the RA802's ability to deformulate the make-up of a transdermal nicotine patch.

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Characterising the polymorphism of active pharmaceutical ingredients when developing a commercially viable product.

Application note: Rapid polymorph identification with the RA802 Pharmaceutical Analyser

Characterising the polymorphism of active pharmaceutical ingredients when developing a commercially viable product.

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This document focuses on concentration measurements but the principles detailed are also applicable to other quantitative measurements, such as stress/strain.

Technical note: Quantitative Raman spectroscopy

This document focuses on concentration measurements but the principles detailed are also applicable to other quantitative measurements, such as stress/strain.

[453kB]

This technology note illustrates the benefits of combining dedicated analysis software with a high-performance Raman instrument and how Renishaw supplies an effective, user-friendly solution to provide complementary information to the multitude of established HTS techniques commercially available.

Technical note: Polymorph identification and qualification

This technology note illustrates the benefits of combining dedicated analysis software with a high-performance Raman instrument and how Renishaw supplies an effective, user-friendly solution to provide complementary information to the multitude of established HTS techniques commercially available.

[552kB]

This note shows how the RA802 Pharmaceutical Analyser can be used to analyse a range of samples, such as powder blends and tablets, to screen for the presence and form of APIs

Application note: Detecting small amounts of multiple API polymorphic forms in powder blends

This note shows how the RA802 Pharmaceutical Analyser can be used to analyse a range of samples, such as powder blends and tablets, to screen for the presence and form of APIs

[237kB]

The ability to group highly similar spectral data is a key result for research areas including biology and medicine. It enables qualitative conclusions to be drawn objectively based on statistics, rather than subjectively based on an analyst’s experience.

Product note: Cluster analysis and data classification

The ability to group highly similar spectral data is a key result for research areas including biology and medicine. It enables qualitative conclusions to be drawn objectively based on statistics, rather than subjectively based on an analyst’s experience.

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Application note detailing how the Virsa Raman analyser can be used to analyse polymer fibres.

Application note: Analysis of polymer fibres using the Virsa™ Raman analyser

Application note detailing how the Virsa Raman analyser can be used to analyse polymer fibres.

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Application note showing how easy it is to analyse liquids with the Virsa Raman analyser

Application note: Analysing liquids with the Virsa™ Raman analyser

Application note showing how easy it is to analyse liquids with the Virsa Raman analyser

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Monitoring the crystallographic phase changes of potassium nitrate using the inVia Raman microscope

Application note: Monitoring phase changes

Monitoring the crystallographic phase changes of potassium nitrate using the inVia Raman microscope

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Application note detailing how the Virsa Raman analyser can be used to study catalysts, with vanadium oxide as an example.

Application note: Analysing catalytic powders with the Virsa™ Raman analyser

Application note detailing how the Virsa Raman analyser can be used to study catalysts, with vanadium oxide as an example.

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